Bi-Shi Fu


Professor, Medical Research Institute, Wuhan University 

Tel:  86-27-68750325

Fax:  86-27-68750325



Bishi Fu, PhD


Research Areas:

Virus-host interactome network, innate immune evasion


Selected Publications: (8 out of 24)

1. Zeng J*, Dong S*, Luo Z*, Xie X*, Fu B*, Li P, Liu C, Yang X, Chen Y, Wang X, Liu Z, Wu J, Yan Y, Wang F, Chen JF, Zhang J, Long G, Li S, Zhao Z, Liang Q (2020). The Zika Virus Capsid Disrupts Corticogenesis by Suppressing Dicer Activity and miRNA Biogenesis. Cell Stem Cell 27(4):618-632.e9.

2. Fu B, Wang L, Li S and Dorf ME (2017). ZMPSTE24 defends against influenza and other pathogenic viruses. J Exp Med 214(4):919-929.

3. Fu B, Zhao M, Wang L, Patil G, Smith J A, Juncadella I J, Zuvela-Jelaska L, Dorf ME, Li S (2017). RNAi Screen and Proteomics Reveal NXF1 as a Novel Regulator of IRF5 Signaling. Sci Rep 7(1):2683.

4. Wang L*, Fu B *, Li W, Patil G, Liu L, Dorf ME, Li S (2017). Comparative influenza protein interactomes identify the role of plakophilin 2 in virus restriction. Nat Commun 8:13876.

5. Fu B, Wang L, Hao D, Schwamborn JC, Li S, Dorf ME (2015). TRIM32 senses and restricts influenza A virus by ubiquitination of PB1 polymerase. PLoS Pathog 11(6):e1004960.

6. Fu B, Kuang E, Li W, Avey D, Li X, Turpin Z, Valdes A, Brulois K, Myoung J, Zhu F (2015). Activation of p90 ribosomal S6 kinases by ORF45 of Kaposi's sarcoma-associated herpesvirus is critical for optimal production of infectious viruses. J Virol 89(1):195-207.

7. Li S*, Wang L.*, Fu B *, Berman MA, Diallo A, Dorf ME (2014). TRIM65 regulates microRNA activity by ubiquitination of TNRC6. P Natl Acad Sci USA 111(19):6970-5.

8. Fu B, Li S, Wang L, Berman MA, Dorf ME (2014). The ubiquitin conjugating enzyme UBE2L3 regulates TNFα-induced linear ubiquitination. Cell Res 24(3):376-9.


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