Education

1993-1997 B.S., Biochemistry, Wuhan University, China

1997-2000 M.S., Molecular Biology, Shanghai Institute of Biochemistry and Cell Biology Chinese Academy of Science, China

2000-2005 Ph.D., Cell and Development Biology, Rutgers, the State University of New Jersey, USA

Academic Experience

2005-2007 Postdoctoral Researcher, Department of Cell Biology and Neurosciences, Rutgers University, USA

2007-2011 Postdoctoral Fellow, Department of Pathology and Laboratory Medicine, Abramson Family Cancer Research Institute, University of Pennsylvania, USA

2011-2015 Professor, Department of Pharmacology, School of Pharmacy, Huazhong University of Science and Technology, China

2016- Professor, Medical Research Institute, Zhongnan Hospital Wuhan University, China

Awards & Honors

National Distinguished Young Scholar (2020)

Provincial Chutian Young Scholar (2018)

Provincial Distinguished Young Scholar (2017)

Lymphoma Research Foundation Fellowship Award (USA) (2008)

Social Service

Chinese Association of Blood Science-Deputy chair

Chinese Association of Pathophysiology (Experimental Hematology)- Broad member

Chinese Anti-Cancer Association (Hematology Oncology)- Broad member

American Association for Cancer Research- Member

International Society of Experimental Hematology- Member

Chinese Society for Cell Biology- Member

Representative Publications

1. Jiang J#, Wang J#, Yue M#, Cai X, Wang T, Wu C, Su H, Wang Y, Han M, Zhang Y, Zhu X, Jiang P, Li P, Sun Y, Xiao W, Feng H, Qing G, Liu H*. Direct Phosphorylation and Stabilization of MYC by Aurora B Kinase Promote T Cell Leukemogenesis. Cancer Cell. 2020, 37(2):200-215.

2. Su H, Hu J, Huang L, Yang Y, Thenoz M, Kuchmiy A, Hu Y, Li P, Feng H, Zhou Y, Taghon T, Van Vlierberghe P, Qing G, Chen Z*, Liu H*. SHQ1 regulation of pre-RNA splicing is required for T-lymphoblastic leukemia cell survival. Nature Communications. 2018,9(1):4281.

3. Wang D#, Yin Z#, Wang H#, Wang L, Li T, Xiao R, Xie T, Han R, Dong R, Liu H*, Liang K*, Qing G*. The Super Elongation Complex Drives Transcriptional Addiction in MYCN-amplified Neuroblastoma. Science Advances. 2023, 9(13): eadf0005.

4. Chen Z^#, Chen C^#, Xiao L^#, Tu R, Yu M, Wang D, Kang W, Han M, Huang H, Liu H*, Zhao B*, Qing G*. HILPS, a Novel Long Non-coding RNA Essential for Global Oxygen Sensing in Human. Science Advances. 2023, 9(47): eadi1867

5. Guo H#, Xu J#, Xing P#, Li Q, Wang D, Tang C, Palhais B, Roels J, Liu J, Pan S, Huang J, Liu Z, Zhu P, Taghon T, Qing G, Van Vlierberghe P*, Liu H*. RNA helicase DHX15 exemplifies a unique dependency in acute leukemia. Haematologica. 2023, 108(8):2029-2043.

6. Hu J#, Wang T#, Xu J, Wu S, Wang L, Su H, Jiang J, Yue M, Wang J, Wang D, Li P, Zhou F, Liu Y, Qing G, Liu H*. WEE1 inhibition induces glutamine addiction in T-cell acute lymphoblastic leukemia. Haematologica. 2021, 106(7):1816-1827.

7. Wu C#, Xie T#, Guo Y, Wang D, Qiu M, Han R, Qing G, Liang K, Liu H*. CDK13 phosphorylates the translation machinery and promotes tumorigenic protein synthesis. Oncogene. 2023, 42(16):1321-1330.

8. Wang J#, Jiang J#, Chen H, Wang L, Guo H, Yang L, Xiao D, Qing G*, Liu H*. FDA-approved drug screen identifies proteasome as a synthetic lethal target in MYC-driven neuroblastoma. Oncogene. 2019, 38(41):6737-6751.

9. Yue M, Jiang J, Gao P, Liu H*, Qing G*. Oncogenic MYC activates a feedforward regulatory loop promoting essential amino acid metabolism and tumorigenesis. Cell Reports. 2017, 21(13): 3819-3832.

10. Wang Z#, Hu Y#, Xiao D, Wang J, Liu C, Xu Y, Shi X, Jiang P, Huang L, Li P, Liu H*, Qing G*. Stabilization of Notch1 by the Hsp90 Chaperon is Crucial for T Cell Leukemogenesis. Clinical Cancer Research. 2017, 23(14):3834-3846.