Education
1995-2000 B.S., Binzhou Medical University, China
2000-2003 M.S., Wuhan University, China
2003-2006 M.D., Wuhan University, China
Academic Experience
2006-2007 Attending Physician, School & Hospital of Stomatology, Wuhan University, China
2007-2012 Associate Professor, Associate Chief Physician, School & Hospital of Stomatology, Wuhan University, China
2009-2012 Postdoctoral Fellow, National Institute of Health, USA
2012-2013 Chief Physician, Associate Professor, School & Hospital of Stomatology, Wuhan University, China
2013- Chief Physician, Professor, School & Hospital of Stomatology, Wuhan University, China
2024- Changjiang Professor, School & Hospital of Stomatology, Wuhan University, China
Awards & Honors
Second Prize of Natural Science of Hubei Province (2019)
First Prize of Scientific and Technological Progress of Shanghai Municipality (2009)
19th International Conference on Oral and Maxillofacial Surgery Outstanding Poster Presentation Award (2009)
Second Prize of the Outstanding Achievement Award in Natural Science of Higher Education Institutions (2015)
First Prize of the Yida Scholarship of the Chinese Stomatological Association (2006)
Social Service
Associate Editor, Oral Diseases (2022-)
Associate Editor, VIEW Medicine (2023-)
Editorial Board Member, Nano TransMed (2021-)
Editorial Board Member, Chinese Journal of Stomatology (2023-)
Editorial Board Member, Int Immunopharmacol (2024-)
Associate Director, Chinese Anti Cancer Association Oral and Maxillofacial Tumor Integrative Medicine Professional Committee (2020-)
Associate Director, Youth Council of China Anti Cancer Association
Representative Publications
1. Zheng DW, Deng WW, Song WF, Wu CC, Liu J, Hong S, Zhuang ZN, Cheng H, Sun ZJ*, Zhang XZ* (2022). Biomaterial-mediated modulation of oral microbiota synergizes with PD-1 blockade in mice with oral squamous cell carcinoma. Nat Biomed Eng 6(1):32-43.
2. Ma X, Li SJ, Liu Y, Zhang T, Xue P, Kang Y, Sun ZJ*, Xu Z* (2022). Bioengineered nanogels for cancer immunotherapy. Chem Soc Rev 51(12):5136-5174.
3. Zhang L, Wan SC, Zhang J, Zhang MJ, Yang QC, Zhang B, Wang WY, Sun J, Kwok RTK, Lam JWY*, Deng H*, Sun ZJ*, Tang BZ* (2023). Activation of Pyroptosis Using AIEgen-Based sp2 Carbon-Linked Covalent Organic Frameworks. J Am Chem Soc 145(32):17689-17699.
4. Ji C, Li H, Zhang L, Wang P, Lv Y, Sun ZJ*, Jie Tan*, Yuan Q*, Tan W (2022). Ferrocene-Containing Nucleic Acid-Based Energy-Storage Nanoagent for Continuously Photo-Induced Oxidative Stress Amplification. Angew Chem Int Ed Engl 61(13):e202200237.
5. Rao L, Bu LL, Ma L,Wang W,Liu H,Wan D, Liu JF, Li A, Guo SS, Zhang L,Zhang WF, Zhao XZ, Sun ZJ*.Liu W* (2018).Platelet-Facilitated Photothermal Therapy of Head and Neck Squamous Cell Carcinoma. Angew Chem Int Ed Engl 57(4):986-91.
6. Wang S, Wang P, Li J, Chen YH*, Sun ZJ*, Lei A* (2023). Electrochemical Flow Aziridination of Unactivated Alkenes. Natl Sci Rev 10(10): nwad187.
7. Wang S, Song A, Xie J, Wang YY, Wang WD, Zhang MJ, Wu ZZ, Yang QC, Li H, Zhang J*, Sun ZJ* (2024). Fn-OMV potentiates ZBP1-mediated PANoptosis triggered by oncolytic HSV-1 to fuel antitumor immunity. Nat Commun 15(1):3669.
8. Zhang L, Song A, Yang QC, Li SJ, Wang S, Wan SC, Sun J, Kwok RTK, Lam JWY*, Deng H*, Tang BZ*, Sun ZJ* (2023). Integration of AIEgens into covalent organic frameworks for pyroptosis and ferroptosis primed cancer immunotherapy. Nat Commun 14(1):5355.
9. Huang B, Tang T, Chen SH, Li H, Sun ZJ*, Zhang ZL*,Zhang MX*, Cui R* (2023). Near-infrared-IIb emitting single-atom catalyst for imaging-guided therapy of blood-brain barrier breakdown after traumatic brain injury. Nat Commun 14(1):197.
10. Tan J, Li H, Ji C, Zhang L, Zhao C, Tang L, Zhang C, Sun ZJ*, Tan W*, Yuan Q* (2022). Electron transfer-triggered imaging of EGFR signaling activity. Nat Commun 13(1):594.
11. Li H, Wang M, Huang B, Zhu SW, Zhou JJ, Chen DR, Cui R*, Zhang M*, Sun ZJ* (2021). Theranostic near-infrared-IIb emitting nanoprobes for promoting immunogenic radiotherapy and abscopal effects against cancer metastasis. Nat Commun 12(1):7149.
12. Rao L, Wu L, Liu Z, Tian R, Yu G, Zhou Z, Yang K, Xiong HG, Zhang A, Yu GT, Sun W, Xu H, Guo J, Li A, Chen H, Sun ZJ*, Fu YX*, Chen X* (2020). Hybrid cellular membrane nanovesicles amplify macrophage immune responses against cancer recurrence and metastasis. Nat Commun 11(1):4909.
13. Su W, Qiu W, Li SJ, Wang S, Xie J, Yang QC, Xu J, Zhang J*, Xu Z*, Sun ZJ* (2023). Dual-Responsive STAT3 Inhibitor Nanoprodrug Combined with Oncolytic Virus Elicits Synergistic Antitumor Immune Responses by Igniting Pyroptosis. Adv Mater 35(11):e2209379.
14. Zhang L, Yang QC, Wang S, Xiao Y, Wan SC, Deng HX*, Sun ZJ* (2022). Engineering Multienzyme-mimicking Covalent Organic Frameworks as Pyroptosis Inducers for Boosting Antitumor Immunity. Adv Mater 34(13):2108174.
15. Ma X, Zhang MJ, Wang J, Zhang T, Xue P, Kang Y, Sun ZJ*, Xu Z* (2022). Emerging Biomaterials Imaging Antitumor Immune Response. Adv Mater 34(42): 2204034.
16. Liang L, Yang LL, Wang W# Ji C, Zhang L, Jia Y, Chen Y, Wang X, Tan J*, Sun ZJ*, Yuan Q* ,Tan W (2021). Calcium Phosphate-Reinforced Metal-Organic Frameworks Regulates Adenosine-Mediated Immunosuppression. Adv Mater 33(45):e2102271.
17. Wang WY, Mo W, Hang Z, Huang Y, Yi H*, Sun ZJ*, Lei AW* (2023). Cuproptosis: Harnessing Transition Metal for Cancer Therapy. ACS Nano 17(20):19581-19599.
18. Zhang L, Xiao Y, Yang QC, Yang LL, Wan SC, Wang S, Zhang L*, Deng HX*, Sun ZJ* (2022). Staggered Stacking Covalent Organic Frameworks for Boosting Cancer Immunotherapy. Adv Funct Mater 32(29):2201542.
19. Chen L, Yang QC, Li YC, Yang LL, Liu JF, Li H, Xiao Y, Bu LL, Zhang WF, Sun ZJ * (2020). Targeting CMTM6 suppresses stem cell -like properties and enhances anti- tumor immunity in head and neck squamous cell carcinoma. Cancer Immunol Res 8(2):179-191.
20. Wu L, Mao L, Liu JF, Chen L, Yu GT, Yang LL, Wu H, Bu LL, Kulkarni AB, Zhang WF, Sun ZJ* (2019). Blockade of TIGIT/CD155 signaling reverses T cells exhaustion and enhances antitumor capability in head and neck squamous cell carcinoma. Cancer Immunol Res 7 (10):1700-13.
