Education
1999-2003 B.S., Wuhan University, China
2004-2010 Ph.D., Wuhan University, China
Academic Experience
2003-2004 Research Assistant, College of Life Sciences, Wuhan University, China
2010-2011 Research Associate, College of Life Sciences, Wuhan University, China
2011-2017 Postdoctoral Fellow, UC San Diego, USA
2017- Professor, Medical Research Institute, Wuhan University, China
2019- PI, Frontier Science Center for Immunology and Metabolism, Wuhan University, China
2022- PI, TaiKang Center for Life and Medical Sciences, Wuhan University, China
Awards & Honors
The national youth talent support program (2022)
Hundred-Talent Program of Hubei Province (2020)
Chutian scholar professor (2019)
Social Service
Young Member of Editorial Board, Science China Life Sciences (2024-)
Representative Publications
1. Du, X.#, Qin W.#, Yang, C., Dai, L., San, M., Xia, Y., Zhou, S., Wang, M., Wu, S., Zhang, S., Zhou, H., Li, S., He, F., Tang, J., Chen, J., Zhou, Y., Xiao, R.* (2024) RBM22 Regulates RNA Polymerase II 5' Pausing, Elongation Rate and Termination by Coordinating 7SK-P-TEFb complex and SPT5. Genome Biology 25, 102. https://doi.org/10.1186/s13059-024-03242-6
2. Du, X., Xiao, R.* (2020) An emerging role of chromatin-interacting RNA-binding proteins in transcription regulation. Essays in Biochemistry 64 (6): 907–918.
3. Van Nostrand, E.#, Freese, P.#, Pratt, G.#, Wang, X.#, Wei, X.#, Xiao, R.#, Blue, S., Chen, J., Cody, N., Dominguez, D., Olson, S., Sundararaman, B, Zhan, L., Bazile, C., Bouvrette, L., Bergalet, J., Duff, M., Garcia, K., Gelboin-Burkhart, C., Hochman, M., Lambert, N., Li, H., Nguyen, T., Palden, T., Rabano, I., Sathe, S., Stanton, R., Su, A., Wang, R., Yee, B., Zhou, B., Louie, A., Aigner, S., Fu, XD*, Lécuyer, E.*, Burge, C.*, Graveley, B.*, Yeo, G.* (2020) A Large-Scale Binding and Functional Map of Human RNA Binding Proteins. Nature 583: 711-719.
4. Xiao, R.#*, Chen, JY#, Liang, Z#, Luo, D., Chen, G., Lu, Z., Chen, Y., Zhou, B., Li, H., Du, X., Yang, Y., San, M., Wei, X., Liu, W., Lecuyer, E., Graveley, B., Yeo, G., Burge, C., Zhang, M., Zhou, Y. and Fu, XD* (2019) Pervasive Chromatin-RNA Binding Protein Interactions Enable RNA-based Regulation of Transcription. Cell. 178(1):107-121.
5. Wei, C.#, Xiao, R.#, Chen, L.#, Cui, H.#, Zhou, Y.#, Xue, Y., Hu, J., Zhou, B., Tsutsui, T., Qiu, J., Li, H., Tang, L. and Fu, XD (2016) RBFox2 Binds Nascent RNA to Globally Regulate Polycomb Complex 2 Targeting in Mammalian Genomes. Molecular Cell. 62(6):875-889.
6. Wang, L.#, Zhou, Y.#, Xu, L.#, Xiao, R.#, Lu, X., Chen, L., Chong, J., He, C., Fu, XD* and Wang, D*. (2015) Molecular basis for 5-carboxycytosine recognition by RNA polymerase II elongation complex. Nature. 523(7562):621-625.
7. Xiao, R.#, Tang, P.#, Yang, B., Huang, J., Zhou, Y., Shao, C., Li, H., Sun, H., Zhang, Y. and Fu, XD (2012) Nuclear matrix factor hnRNP U/SAF-A exerts a global control of alternative splicing by regulating U2 snRNP maturation. Molecular Cell. 45(5):656-668.
