FACULTY

Guohua Yuan

Final Degree:PhD

Professional Title:Professor

Major:Oral medicine

Research Direction:Tooth development and regeneration

Email:yuanguohua[at]whu.edu.cn

Tel:86-27-87686211

Detailed Introduction

Education

1999-2004 DDS, Sichuan University, China

2004-2006 Master, Wuhan University, China

2006-2009 Ph.D, Wuhan University, China

2007-2009 Joint Ph.D Training, The University of Texas Health Science Center at San Antonio, USA

Academic Experience

2011-2017 Associate professor, Wuhan University, China

2012-2014 Postdoctoral Fellow, Tulane University, USA

2018- Professor, Wuhan University, China

Representative Publications

  1. Zheng H, Zhang X, Fu J, Xue Y, Chen Z, Yang G, Chen Y, Chen D, Yuan G.* CHIP inhibits odontoblast differentiation through promoting DLX3 polyubiquitylation and degradation. Development 2023;150(10). DOI: 10.1242/dev.200848

  2. Zheng H, Fu J, Chen Z, Yang G, Yuan G*. 2022. Dlx3 ubiquitination by nuclear mdm2 is essential for dentinogenesis in mice. J Dent Res. 2022;101(9):1064-1074.

  3. Fu J, Zheng H, Xue Y, Jin R, Yang G, Chen Z, Yuan G*. WWP2 Promotes Odontoblastic Differentiation by Monoubiquitinating KLF5. J Dent Res. 2021;100(4):432-439.

  4. Zheng H, Yang G, Fu J, Chen Z, Yuan G*. Mdm2 Promotes Odontoblast-like Differentiation by Ubiquitinating Dlx3 and p53. J Dent Res. 2020;99(3):320-328.

  5. Yuan G, Yang G, Zheng Y, Zhu X, Chen Z, Zhang Z, Chen Y*. The Non-canonical BMP and Wnt/β-catenin Signaling Pathways Orchestrate Early Tooth Development. Development. 2015;142(1):128-139.

  6. Yuan G, Zhang L, Zhang Y, Fan M Bian Z, Chen Z*. Mesenchyme is Responsible for Tooth Suppression in the Mouse Lower Diastema. J Dent Res. 2008;87(4):386-390


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