学习经历
2007-2009 加拿大约克大学生物技术专业,学士
2010-2011 澳大利亚昆士兰大学分子生物学,硕士
2012-2016 澳大利亚昆士兰大学神经生物学,博士
工作经历与任职
2020-至今 武汉大学中南医院神经外科,教授/博士生导师
研究方向
恐惧记忆,表观遗传学,应激障碍相关心理疾病
获奖与荣誉
福建省闽江学者讲座教授人才计划,2023年
科创中国湖北省科技经济融合优秀项目二等奖,2023年
武汉英才计划-产业领军人才计划入选者,2022年
国家海外高层次青年人才引进计划入选者,2021年
湖北省BR计划,青年计划入选者,2019年
澳大利亚优秀青年科学家奖,2019年
亚太地区神经科学学会青年科学家奖 (Mark Rowe),2019年
代表性论文
1. Wei W, Zhao Q, Wang Z, Liau WS, Basic D, Ren H, Marshall PR, Zajaczkowski EL, Leighton LJ, Madugalle SU, Musgrove M, Periyakaruppiah A, Shi J, Zhang J, Mattick JS, Mercer TR, Spitale RC, Li X*, Bredy TW*. (2023)ADRAM is an experience-dependent long noncoding RNA that drives fear extinction through a direct interaction with the chaperone protein 14-3-3. Cell Rep. 38(12). (*共同讯)
2. Long S, Yan Y, Xu H, Wang L, Jiang J, Xu Z, Liu R, Zhou Q, Huang X, Chen J, Li Z, Wei W*, Li X*. (2023) Insights into the regulatory role of RNA methylation modifications in glioma. J Transl Med. 14;21(1):810.
3. Li X*, Zhao QY, Wei W, Lin Q, Magnan C, Emami M, Wearick-Silva L, Viola T, Grassi-Oliveira R, Marshall P, Yin JY, Nainar S, Vågbø CB, Leighton LJ, Zajaczkowski EL, Bjørås M, Baldi P, Spitale RC and Bredy TW* (2019). The DNA modification N6-methyl-2’-deoxyadenosine (m6dA) drives activity-induced gene expression and is required for fear extinction. Nature Neuroscience, 22(4): 534-544.
4. LI X, Marshall P, Leighton LJ, Zajaczkowski EL, Bredy TW, and Wei W (2018). The DNA Repair-Associated Protein Gadd45r Regulates the Temporal Coding of Immediate Early Gene Expression within the Prelimbic Prefrontal Cortex and Is Required for the Consolidation of Associative Fear Memory. Journal of Neuroscience, 39(6): 970-983.
5. Chen T*, Wei W*, Zhang J*, Yu J, Xu S, Wu D, Li X*, Chen J*. (2023) Assessment of plasma soluble Tie-2 level to distinguish moyamoya disease from atherosclerotic cerebrovascular disease and predict postoperative neovascularization. J Neurosurg.16:1-10.
6. Li X, Wei W, Zhao QY, Baker-Andresen D, Flavell CR, Widagdo J, D'Alessio A, Zhang Y and Bredy TW (2014a). Neocortical Tet3-mediated hydroxymethylation promotes rapid behavioural adaptation. Proceedings of the National Academy of Sciences, 111(19), 7120-5. (*Faculty of 1000 recommended*)