科学研究
CaMK modulates sensory neural activity to control longevity and proteostasis
2025-05-14Chemical-based epigenetic reprogramming to advance pluripotency and totipotency
2025-04-18Hypoxia-induced phase separation of ZHX2 alters chromatin looping to drive cancer metastasis
2025-04-03TOPO-seq reveals DNA topology-induced off-target activity by Cas9 and base editors
2025-04-03An epitranscriptomic program maintains skeletal stem cell quiescence via a METTL3-FEM1B-GLI1 axis
2025-02-28KRAS4B oncogenic mutants promote non-small cell lung cancer progression via the interaction of deubiquitinase USP25 with RNF31
2025-02-14Diverse microtubule-binding repeats regulate TPX2 activities at distinct locations within the spindle
2025-01-17The epitranscriptional factor PCIF1 orchestrates CD8+ T cell ferroptosis and activation to govern anti-tumor immunity
2025-01-07A noncoding variant confers pancreatic differentiation defect and contributes to diabetes susceptibility by recruiting RXRA
2024-11-12A subset of neutrophils activates anti-tumor immunity and inhibits non-small-cell lung cancer progression
2024-11-07Selective translation of nuclear mitochondrial respiratory proteins reprograms succinate metabolism in AML development and chemoresistance
2024-10-01Epitope prime editing shields hematopoietic cells from CD123 immunotherapy for acute myeloid leukemia
2024-10-01Rapid generation of long, chemically modified pegRNAs for prime editing
2024-09-30Amplification editing enables efficient and precise duplication of DNA from short sequence to megabase and chromosomal scale
2024-07-25Minimizing the ratio of ionizable lipid in lipid nanoparticles for in vivo base editing
2024-05-24
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