科学研究
Hypoxia-induced phase separation of ZHX2 alters chromatin looping to drive cancer metastasis
2025-04-03Diverse microtubule-binding repeats regulate TPX2 activities at distinct locations within the spindle
2025-01-17The epitranscriptional factor PCIF1 orchestrates CD8+ T cell ferroptosis and activation to govern anti-tumor immunity
2025-01-07A noncoding variant confers pancreatic differentiation defect and contributes to diabetes susceptibility by recruiting RXRA
2024-11-12A subset of neutrophils activates anti-tumor immunity and inhibits non-small-cell lung cancer progression
2024-11-07Selective translation of nuclear mitochondrial respiratory proteins reprograms succinate metabolism in AML development and chemoresistance
2024-10-01Epitope prime editing shields hematopoietic cells from CD123 immunotherapy for acute myeloid leukemia
2024-10-01Rapid generation of long, chemically modified pegRNAs for prime editing
2024-09-30Amplification editing enables efficient and precise duplication of DNA from short sequence to megabase and chromosomal scale
2024-07-25Minimizing the ratio of ionizable lipid in lipid nanoparticles for in vivo base editing
2024-05-24USP8-governed GPX4 homeostasis orchestrates ferroptosis and cancer immunotherapy
2024-04-10UFL1 ablation in T cells suppresses PD-1 UFMylation to enhance anti-tumor immunity
2024-03-21Therapeutic targeting nudix hydrolase 1 creates a MYC-driven metabolic vulnerability
2024-03-16Ptip safeguards the epigenetic control of skeletal stem cell quiescence and potency in skeletogenesis
2024-02-29Fast and sensitive CRISPR detection by minimized interference of target amplification
2024-02-08
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