学习经历
1996-2001 武汉大学临床医学院,学士
2001-2006 复旦大学生命科学院神经所,博士
工作经历与任职
2006-2010 美国爱因斯坦医学院神经所,博士后
2010-2014 武汉大学人民医院,副教授
2010-2018 武汉大学眼科研究所,副所长
2016-2018 武汉大学人民医院,副院长
2016-2016 美国斯坦福大学,高级访问学者
2014- 武汉大学人民医院,教授
2018- 武汉大学眼科研究所,所长
2018- 武汉大学人民医院眼科中心,常务副主任
研究方向
神经眼科,遗传性眼病
获奖与荣誉
中国车谷英才计划人才(2022)
湖北省科技进步奖(2021)
中华医学会视觉生理组突出贡献奖(2018)
青春武昌代言人(2017)
湖北省荆楚楷模(2017)
湖北省青年五四奖章(2017)
武汉大学珞珈特聘教授 (2016)
湖北省科协创新创业人才(2015)
武汉大学五四青年奖章(2015)
武汉市中青年医学骨干人才(2014)
湖北省青年科技晨光计划人才(2014)
湖北省杰出青年基金(2014)
湖北省青年科技奖(2012)
武汉大学珞珈青年学者(2011)
代表性论文
1. Zhou LB, Chen LJ, Chen SJ, Pu ZY, Gu MJ*, Shen Y*. Highly Efficient Photodynamic Therapy with Mitochondria‐Targeting Aggregation‐Induced Emission Photosensitizer for Retinoblastoma. Advanced Healthcare Materials.2022 Oct 22:e2202219
2. Chen F, Duan XD, Yu Y, Yang S, Chen YY, Gee CE, Nagel G, Zhang K*, Gao SQ*, Shen Y* . Visual function restoration with a highly sensitive and fast Channelrhodopsin in blind mice. Signal Transduction and Targeted Therapy.2022 Apr 18;7(1):104.
3. Liu Y , Xia P, Yan F , Yuan M, Yuan H, Du Y , Yan J, Song Q, Zhang T , Hu D , Shen Y*.Engineered Extracellular Vesicles for Delivery of an IL-1 Receptor Antagonist Promote Targeted Repair of Retinal Degeneration.Small.2023 Nov 19(46):e2302962
4. Shen Y, Luo X, Liu S, Shen Y, Nawy S, Shen Y*. Rod bipolar cells dysfunction occurs before ganglion cells loss in excitotoxin-damaged mouse retina. Cell Death Dis.2019 Dec 2;10(12):905.
5. Wu M, Deng Q, Lei X, Du Y, Shen Y*. Elavl2 Regulates Retinal Function Via Modulating the Differentiation of Amacrine Cells Subtype.Invest Ophthalmol Vis Sci.2021 Jun 1;62(7):1.
6. Man Yuan,Sen Jin,Gao Tan, Siyuan Song, Yizong Liu, Huadong Wang, Shen Y*. A Non‑canonical Excitatory PV RGC–PV SC Visual Pathway for Mediating the Looming‑evoked Innate Defensive Response.Neurosci Bull.2023
7. Feiyue Yan, Yizong Liu , Tianlu Zhang and Yin Shen*. Identifying TNF and IL6 as potential hub genes and targeted drugs associated with scleritis: A bio-informative report.Frontiers in Immunology.2023
8. Yan J, Li Y, Zhang T,Shen Y*. Numb deficiency impairs retinal structure and visual function in mice. Exp Eye Res. 2022 Jun;219:109066. 2022 Apr 15.
9. Li Y, Shen Y, Cai D, Shen Y*. Sox2 knockdown in the neonatal retina causes cell fate to switch from amacrine to bipolar.Brain Res. 2021 Feb 1;1752:147265.
10. Zhao Q, Kong Y, Kittredge A, Li Y,Shen Y*, Zhang Y, Tsang SH, Yang T.Distinct expression requirements and rescue strategies for <i>BEST1</i> loss-and gain-of-function mutations. Elife. 2021 Jun 1;10:e67622.
11. Zhi Li,Tao He, Ke Du,Yi-Qiao Xing,Yuan-Min Run,Ying Yan, Yin Shen*. Overexpression of 15-lipoxygenase-1 in oxygen-induced ischemic retinopathy inhibits retinal neovascularization via downregulation of vascular endothelial growth factor-A expression. Mol Vis. 2021;210
12. Tong Y, Huang X, Qi CX, Shen Y*. Altered Functional Connectivity of the Primary Visual Cortex in Patients With Iridocyclitis and Assessment of Its Predictive Value Using Machine Learning. Front Immunol. 2021 May 7;12:660554.