Education

2001-2005 B.S., School of Life Sciences, Peking University, China

2005-2011 Ph.D., Institute of Microbiology, Chinese Academy of Sciences

Academic Experience

2011-2018 Postdoctoral Fellow, Department of Molecular Microbiology and Immunology, University of Southern California, USA

2018- Professor, Medical Research Institute, Wuhan University, China

2018- Principal investigator, State Key Laboratory of Virology, Wuhan University, China

Representative Publications

1. Yaru Zhou, Xuezhang Tian, Shaowei Wang, Ming Gao, Chuchu Zhang, Jiali Ma, Xi Cheng, Lei Bai, Hai-Bin Qin, Min-Hua Luo, Qingsong Qin, Baishan Jiang, Ke Lan, Junjie Zhang*. (2024) Palmitoylation of KSHV pORF55 is required for Golgi localization and efficient progeny virion production. PLoS Pathogens 20 (4), e1012141

2. Shaowei Wang, Xuezhang Tian, Yaru Zhou, Jun Xie, Ming Gao, Yunhong Zhong, Chuchu Zhang, Keying Yu, Lei Bai, Qingsong Qin, Bo Zhong, Dandan Lin, Pinghui Feng, Ke Lan, Junjie Zhang*. (2024) Non-canonical regulation of the reactivation of an oncogenic herpesvirus by the OTUD4-USP7 deubiquitinases. PLoS Pathogens 20 (1), e1011943

3. Shuo Wang, An Song, Jun Xie, Yuan-Yuan Wang, Wen-Da Wang, Meng-Jie Zhang, Zhi-Zhong Wu, Qi-Chao Yang, Hao Li, Junjie Zhang*, Zhi-Jun Sun*. (2024) Fn-OMV potentiates ZBP1-mediated PANoptosis triggered by oncolytic HSV-1 to fuel antitumor immunity. Nature communications 15 (1), 3669

4. Liting Zhang, Congqing Jiang, Yunhong Zhong, Kongliang Sun, Huiru Jing, Jiayu Song, Jun Xie, Yaru Zhou, Mao Tian, Chuchu Zhang, Xiaona Sun, Shaowei Wang, Xi Cheng, Yuelan Zhang, Wei Wei, Xiang Li, Bishi Fu, Pinghui Feng, Bing Wu, Hong-Bing Shu, Junjie Zhang*. (2023) STING is a cell-intrinsic metabolic checkpoint restricting aerobic glycolysis by targeting HK2. Nature Cell Biology (25). 1208–1222

5. Xuezhang Tian, Yaru Zhou, Shaowei Wang, Ming Gao, Yanlin Xia, Yangyang Li, Yunhong Zhong, Wenhao Xu, Lei Bai, Bishi Fu, Yu Zhou, Hye-Ra Lee, Hongyu Deng, Ke Lan, Pinghui Feng, Junjie Zhang*. (2023) Genome-Wide CRISPR-Cas9 Screen Identifies SMCHD1 as a Restriction Factor for Herpesviruses. mBio 14 (2). e00549-23

6. Jun Xie, Shaowei Wang, Yunhong Zhong, Ming Gao, Xuezhang Tian, Liting Zhang, Dongli Pan, Qingsong Qin, Bing Wu, Ke Lan, Zhi-Jun Sun, Junjie Zhang*. (2023) Oncolytic herpes simplex virus armed with a bacterial GBP1 degrader improves antitumor activity. Molecular Therapy-Oncolytics (29). 61–76

7. Wen Su, Wei Qiu, Shu-Jin Li, Shuo Wang, Jun Xie, Qi-Chao Yang, Jiming Xu, Junjie Zhang*, Zhigang Xu*, Zhi-Jun Sun*. (2022) A Dual-Responsive STAT3 Inhibitor Nanoprodrug Combined with Oncolytic Virus Elicits Synergistic Antitumor Immune Responses by Igniting Pyroptosis. Advanced Materials 35 (11). 2209379

8. Xiaona Sun, Ting Liu, Jun Zhao, Hansong Xia, Jun Xie, Yu Guo, Li Zhong, Mi Li, Qing Yang, Cheng Peng, Isabelle Rouvet, Alexandre Belot, Hong-Bing Shu, Pinghui Feng*, Junjie Zhang*. (2020) DNA-PK deficiency potentiates cGAS-mediated antiviral innate immunity. Nature communications 11 (1). 1-15