Education

2001. 9-2005.6 B.S. College of Life Science, Wuhan University

2005.9-2010.6 Ph.D College of Life Science, Wuhan University

Academic Experience

2010-2014 Lecturer, College of Life Science, Wuhan University

2014-2016 Associated Professor, College of Life Science, Wuhan University

2016-2019 Associated Professor, Medical Research Institute, Wuhan University

2019- Professor, Medical Research Institute, Wuhan University

2019- Professor, Frontier Science Center for Immunology and Metabolism, Wuhan University, China

Representative Publications

1. Liu R, Zeng LW, Li HF, Shi JG, Zhong B, Shu HB*, Li S* (2023). PD-1 signal negatively regulates the common cytokine receptor g chain via MARCH5-mediated ubiquitination and degradation to suppress anti-tumor immunity. Cell Res. 33(12):923-939.

2. Yi XM, Li M, Chen YD, Shu HB, Li S*(2022). Reciprocal regulation of IL-33 receptor-mediated inflammatory response and pulmonary fibrosis by TRAF6 and USP38. PNAS. 119(10):e2116279119.

3. Liu R, Zeng LW, Gong R, Yuan F, Shu HB, Li S* (2021). mTORC1 activity regulates post-translational modifications of glycine decarboxylase to modulate glycine metabolism and tumorigenesis. Nat Commun.12 (1):4227.

4. Zeng LW, Feng L, Liu R, Lin H, Shu HB, Li S* (2022). The membrane-associated ubiquitin ligases MARCH2 and MARCH3 target IL-5 receptor alpha to negatively regulate eosinophilic airway inflammation. Cell Mol Immunol. doi: 10.1038/s41423-022-00907-9.

5. Lian H, Zang R, Wei J, Ye W, Hu MM, Chen YD, Zhang XN, Guo Y, Lei CQ, Yang Q, Luo WW, Li S*, Shu HB* (2018). The Zinc-Finger Protein ZCCHC3 Binds RNA and Facilitates Viral RNA Sensing and Activation of the RIG-I-like Receptors. Immunity. 18; 49 (3):438-448.