RESEARCH

Yin Shen

Final Degree:M.D.& Ph.D

Professional Title:Professor

Major:Ophthalmology

Research Direction:Neuro-ophthalmology & Inherited Retina Disease

Email:yinshen[at]whu.edu.cn

Tel:

Detailed Introduction

Education

2001-2006 Ph.D Fudan University, Shanghai, China

1996-2001 M.D. Wuhan University, Wuhan, China

Academic Experience

2006-2010 Research Associate, Einstein College of Medicine

2010-2014 Associate Professor, Renmin Hospital of Wuhan University

2014- Professor, Renmin Hospital of Wuhan University

2017-2019 Vice President, Renmin Hospital of Wuhan University

2019- Director, Eye Institute of Wuhan University

Executive Deputy Director, Eye Center of Renmin Hospital

Awards & Honors

Luojia Young Scholar of Wuhan University(2011)

Youth Science and Technology Award of Hubei Province(2012)

Outstanding Medical Award of Wuhan University(2012)

Young Talent of Medical Science(2013)

The Outstanding Young Scientist of Hubei Province(2014)

Hubei Province Youth Science and Technology Plan(2014)

Innovation and Entrepreneurial Talent for Science and Technology, Association of Hubei Province(2015)

Luojia Professor of Wuhan University(2016)

Wuhan Youth Science and Technology Plan (2016)

Youth medal of Hubei Province(2017)

Science and Technology Progress Award of Hubei Province(2021)

Chegu Talent of Wuhan (2022)

Representative Publications

  1. Zhou LB, Chen LJ, Chen SJ, Pu ZY, Gu MJ*, Shen Y*. Highly Efficient Photodynamic Therapy with Mitochondria‐Targeting Aggregation‐Induced Emission Photosensitizer for Retinoblastoma. Advanced Healthcare Materials.2022 Oct 22:e2202219

  2. Chen F, Duan XD, Yu Y, Yang S, Chen YY, Gee CE, Nagel G, Zhang K*, Gao SQ*, Shen Y* . Visual function restoration with a highly sensitive and fast Channelrhodopsin in blind mice. Signal Transduction and Targeted Therapy.2022 Apr 18;7(1):104.

  3. Liu Y , Xia P, Yan F , Yuan M, Yuan H, Du Y , Yan J, Song Q, Zhang T , Hu D , Shen Y*.Engineered Extracellular Vesicles for Delivery of an IL-1 Receptor Antagonist Promote Targeted Repair of Retinal Degeneration.Small. 2023 Nov 19(46):e2302962

  4. Shen Y, Luo X, Liu S, Shen Y, Nawy S, Shen Y*. Rod bipolar cells dysfunction occurs before ganglion cells loss in excitotoxin-damaged mouse retina. Cell Death Dis.2019 Dec 2;10(12):905.

  5. Wu M, Deng Q, Lei X, Du Y, Shen Y*. Elavl2 Regulates Retinal Function Via Modulating the Differentiation of Amacrine Cells Subtype.Invest Ophthalmol Vis Sci.2021 Jun 1;62(7):1.

  6. Man Yuan,Sen Jin,Gao Tan, Siyuan Song, Yizong Liu, Huadong Wang, Shen Y*. A Non‑canonical Excitatory PV RGC–PV SC Visual Pathway for Mediating the Looming‑evoked Innate Defensive Response.Neurosci Bull.2023

  7. Feiyue Yan, Yizong Liu , Tianlu Zhang and Yin Shen*. Identifying TNF and IL6 as potential hub genes and targeted drugs associated with scleritis: A bio-informative report.Frontiers in Immunology.2023

  8. Yan J, Li Y, Zhang T,Shen Y*. Numb deficiency impairs retinal structure and visual function in mice. Exp Eye Res. 2022 Jun;219:109066. 2022 Apr 15.

  9. Li Y, Shen Y, Cai D, Shen Y*. Sox2 knockdown in the neonatal retina causes cell fate to switch from amacrine to bipolar.Brain Res. 2021 Feb 1;1752:147265.

  10. Zhao Q, Kong Y, Kittredge A, Li Y,Shen Y*, Zhang Y, Tsang SH, Yang T.Distinct expression requirements and rescue strategies for <i>BEST1</i> loss-and gain-of-function mutations. Elife. 2021 Jun 1;10:e67622.

  11. Zhi Li,Tao He, Ke Du,Yi-Qiao Xing,Yuan-Min Run,Ying Yan, Yin Shen*. Overexpression of 15-lipoxygenase-1 in oxygen-induced ischemic retinopathy inhibits retinal neovascularization via downregulation of vascular endothelial growth factor-A expression. Mol Vis. 2021;210

  12. Tong Y, Huang X, Qi CX, Shen Y*. Altered Functional Connectivity of the Primary Visual Cortex in Patients With Iridocyclitis and Assessment of Its Predictive Value Using Machine Learning. Front Immunol. 2021 May 7;12:660554.


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