RESEARCH

Li Wang

Final Degree:PhD

Professional Title:Professor

Major:Cell biology

Research Direction:Cellular reprogramming and regenerative medicine

Email:liwang2020[at]whu.edu.cn

Tel:

Detailed Introduction

Education

2002-2006 B.S., Huazhong Normal University, Wuhan, China

2006-2012 Ph.D., Institute of Biophysics, Chinese Academy of Sciences, Beijing, China

2013-2018 Postdoctoral Research Associate, McAllister Heart Institute, University of North Carolina at Chapel Hill, NC, US

2018-2020 Research Associate, McAllister Heart Institute, University of North Carolina at Chapel Hill, NC, US

2020-Present Professor, Wuhan University

Awards & Honors

Career Development Awards, American Heart Association (2018)

Representative Publications

  1. Mengxin Liu; Jie Liu; Tong Zhang; Wang L. Direct cardiac reprogramming: Toward the era of multi-omics analysis, Cell Insight, 2022, 1(6)

  2. Wang L*, Yang Y*, Ma H, Xie Y, Near D, Xu Y, Garbutt T, Li Y, Liu J, Qian L. Single Cell Dual-Omics of Cardiac Non-myocyte Reveals Their Functional States at Transcriptome and Epigenome Levels. Cardiovascular Research, 2022 May 6;118(6):1548-1563.

  3. Wang L, Ma H, Huang P, Xie Y, Near D, Wang H, Xu J, Yang Y, Xu Y, Garbutt T, Zhou Y, Liu Z, Yin C, Bressan M, Taylor JM, Liu J, Qian L. Down-regulation of Beclin1 promotes direct cardiac reprogramming. Science Translational Medicine, 2020 Oct 21;12(566):eaay7856.

  4. Wang, L., Huang, P., Near, D., Ravi, K., Xu, Y., Yin, C., Liu, J. and Qian, L. Isoform Specific Effects of Mef2C during Direct Cardiac Reprogramming. Cells, 2020 Jan 22;9(2):268.

  5. Liu Z*., Wang L.*, Welch J.*, Ma H., Zhou Y., Vaseghi H.R., Yu S., Wall J.B., Alimohamadi S., Zheng M., Yin C., Shen W., Prins J., Liu J.and Qian L. Single-cell transcriptomics reconstructs fate conversion from fibroblast to cardiomyocyte. Nature, 2017 Nov 2;551(7678):100-104. * Equal contribution

  6. Wang L. *, Liu Z. *, Yin C., Asfour H., Chen O., Li Y., Bursac N., Liu J. and Qian L. Stoichiometry of Gata4, Mef2c and Tbx5 influences the efficiency and quality of iCM reprogramming. Circ Res. 2015 Jan 16;116(2):237-44 * Equal contribution. (Editor’s Pick; highlighted on cover; Previewed in Muraoka et al., Circ Res, 116:216-218.)


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