FACULTY

Xinghuan Wang

Final Degree:PhD

Professional Title:Professor

Major:Tumor Biology, Urology

Research Direction:Bladder Cancer, Prostate Cancer

Email:wangxinghuan[at]whu.edu.cn

Tel:86-27-67812888

Detailed Introduction

Education

1981-1986 B.S., Wuhan University, China

1986-1989 M.S., Wuhan University, China

1993-1996 Ph.D., Peking University, China

Academic Experience

1989-1993 Attending Physician, Department of Urology, Zhongnan Hospital of Wuhan University, China

1996-1998 Associate Chief Physician, Department of Urology, Guangdong General Hospital, China

2008-2023 Professor and Director, Department of Urology, Zhongnan Hospital of Wuhan University, China

2015- Professor and Dean, Zhongnan Hospital of Wuhan University, China

2019- Professor and Dean, Institute of Urology, Wuhan University, China

Awards & Honors

1st, Second Prize of National Award for Technological Invention (2019)

Wu Jie-Ping Medical Innovation Award (2020)

Social Service

Director, Urological Association of Chinese Research Hospital Association (2016-)

Vice Director, Urological Association of Chinese Research Hospital Association (2019-)

Member, Academic Degrees Committee of the State Council (2020-)

Representative Publications

1.Xiao Y, Jin W, Ju L, Fu J, Wang G, Yu M, Chen F, Qian K, Wang X*, Zhang Y* (2024). Tracking single-cell evolution using clock-like chromatin accessibility loci. Nat Biotechnol. doi: 10.1038/s41587-024-02241-z. Epub ahead of print.

2.Wang Y, Ju L, Wang G, Qian K, Jin W, Li M, Yu J, Shi Y, Wang Y, Zhang Y*, Xiao Y*, Wang X* (2023). DNA polymerase POLD1 promotes proliferation and metastasis of bladder cancer by stabilizing MYC. Nat Commun 14:2421.

3.Xiao Y, Jin W, Qian K, Ju L, Wang G, Wu K, Cao R, Chang L, Xu Z, Luo J, Shan L, Yu F, Chen X, Liu D, Cao H, Wang Y, Cao X, Zhou W, Cui D, Tian Y, Ji C, Luo Y, Hong X, Chen F, Peng M, Zhang Y, Wang X* (2024). Integrative Single Cell Atlas Revealed Intratumoral Heterogeneity Generation from an Adaptive Epigenetic Cell State in Human Bladder Urothelial Carcinoma. Adv Sci (Weinh) 11:e2308438.

4.Yan P, Wang G, Huang M, Liu Z, Dai C, Hu B, Gu M, Deng Z, Liu R, Wang X*, Liu T* (2024). Combinatorial Biosynthesis Creates a Novel Aglycone Polyether with High Potency and Low Side Effects Against Bladder Cancer. Adv Sci (Weinh) :e2404668.

5.Zhou F, Deng Z, Shen D, Lu M, Li M, Yu J, Xiao Y, Wang G, Qian K, Ju L*, Wang X* (2024). DLGAP5 triggers proliferation and metastasis of bladder cancer by stabilizing E2F1 via USP11. Oncogene 43:594-607.

6.Yu J, Li M, Ju L, Zhou F, Wang Y, Zhang Y, Zhang R, Du W, Huang R, Qian K, Wang G, Xiao Y*, Wang X* (2024). TRAIP suppresses bladder cancer progression by catalyzing K48-linked polyubiquitination of MYC. Oncogene 43:470-483.

7.Liu W, Shen D, Ju L, Zhang R, Du W, Jin W, Xiong K, Wang G, Qian K, Zhang Y*, Xiao Y*, Wang X* (2022). MYBL2 promotes proliferation and metastasis of bladder cancer through transactivation of CDCA3. Oncogene 41:4606-4617.


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