FACULTY

Yanggan Wang

Final Degree:M.D., Ph.D.

Professional Title:Professor

Major:Cardiovascular disease

Research Direction:Heart failure, Arrhythmias

Email:Wb000813[at]whu.edu.cn

Tel:86-027-67813477

Detailed Introduction

Education

MD: Tongji Medical University, China, 1986.

PhD: Tongji Medical University, China, 1995

Positions/Employment

1986-1990: Physician, Tongji Hospital, Tongji Medical University, Department of Cardiology, China.

1995-1996: Chief physician, Tongji Hospital, Tongji Medical University, Department of Cardiology, China.

1996-1998: Post-doctoral Fellow, Technical University of Munich, Division of Cardiology, Department of Internal Medicine, Germany.

1998- 2001: Post-doctoral Fellow, Division of Cardiology, Department of Pediatrics, Emory University, Atlanta, USA.

2001-2003: Instructor, Division of Cardiology, Department of Pediatrics, Emory University, Atlanta, USA.

2003-2007: Assistant professor, Division of Cardiology, Department of Internal Medicine, University of Texas Southwestern Medical Center at Dallas. USA

2007-2011: Tenure-track Assistant Professor, Director of Heart Failure Research Center, Division of Cardiology, Department of Pediatrics, Emory University, Atlanta, USA.

2012-: Professor of Department of Cardiology, Zhongnan Hospital of Wuhan University & Professor of Medical Research Institute of Wuhan University, China

Research interests

Mechanisms of cardiac calcium regulation disorder,structural and electrical remodeling in heart failure.

Awards and honors

Hubei Chutian Scholar Chair Professor

Hubei Science and Technology Progress Prize

Representative publications

  1. Lei Q, Yu Z, Li H, Cheng J, Wang Y*. Fatty acid-binding protein 5 aggravates pulmonary artery fibrosis in pulmonary hypertension secondary to left heart disease via activating wnt/β-catenin pathway. Journal of Advanced Research, 2022 Sep;40:197-206.

  2. Zhang G, Wang X, Bi X, Li C, Deng Y, Al-Hashimi A, Luo X, Gillette T, Austin R, Wang Y*, Wang Z*. GRP78 (Glucose-RegulatedProtein of 78 kDa) Promotes Cardiomyocyte Growth Through Activation of GATA4 (GATA-Binding Protein 4). Hypertension, 2019, 73(2): 390-398.

  3. Keskanokwong T, Lim H, Zhang P, Cheng J, Xu L, Lai D, Wang Y*. Dynamic Kv4.3-CaMKII unit in heart: an intrinsic negative regulator for CaMKII activation. European Heart Journal, 2011, 32(3): 305-315.

  4. Xu L; Lai D, Cheng J, Lim H J, Keskanokwong T, Backs Johannes, Olson Eric N, Wang Yanggan*. Alterations of L-type calcium current and cardiac function in CaMKIIδ knockout mice. Circulation Research, 2010, 107(3): 398-407.

  5. Wang Y*, Cheng J, Joyner RW, Wagner MB, Hill JA. Remodeling of early-phase repolarization: a mechanism of abnormal impulse conduction in heart failure. Circulation. 2006 Apr 18;113(15):1849-56.


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