科学研究
Small molecule activation of NOTCH signaling inhibits acute myeloid leukemia.
2016-11-15USP18 recruits USP20 to promote innate antiviral response through deubiquitinating STING/MITA
2016-11-03Polo-like Kinase-1 Regulates Myc Stabilization and Activates a Feedforward Circuit Promoting Tumor Cell Survival.
2016-10-26Sumoylation Promotes the Stability of the DNA Sensor cGAS and the Adaptor STING to Regulate the Kinetics of Response to DNA Virus.
2016-10-21MSX1 Modulates RLR-Mediated Innate Antiviral Signaling by Facilitating Assembly of TBK1-Associated Complexes.
2016-10-21The Type I Interferon-IRF7 Axis Mediates Transcriptional Expression of Usp25 Gene.
2016-10-21LSm14A Plays a Critical Role in Antiviral Immune Responses by Regulating MITA Level in a Cell-Specific Manner.
2016-10-21The VP3 structural protein of foot-and-mouth disease virus inhibits the IFN-β signaling pathway.
2016-10-21Foot-and-mouth disease virus structural protein VP3 degrades Janus kinase 1 to inhibit IFN-γ signal transduction pathways.
2016-10-21iRhom2 is essential for innate immunity to DNA viruses by mediating trafficking and stability of the adaptor STING.
2016-07-25The tumor suppressor PTEN has a critical role in antiviral innate immunity
2015-12-21Myc promotes glutaminolysis in human neuroblastoma through direct activation of glutaminase 2
2015-12-01TRIM38 Negatively Regulates TLR3/4-Mediated Innate Immune and Inflammatory Responses by Two Sequential and Distinct Mechanisms
2015-11-01Metabolic targeting of oncogene MYC by selective activation of the proton-coupled monocarboxylate family of transporters
2015-10-05Parafibromin Is a Component of IFN-γ-Triggered Signaling Pathways That Facilitates JAK1/2-Mediated Tyrosine Phosphorylation of STAT1
2015-09-15
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