科学研究
Minimizing the ratio of ionizable lipid in lipid nanoparticles for in vivo base editing
2024-05-24USP8-governed GPX4 homeostasis orchestrates ferroptosis and cancer immunotherapy
2024-04-10UFL1 ablation in T cells suppresses PD-1 UFMylation to enhance anti-tumor immunity
2024-03-21Therapeutic targeting nudix hydrolase 1 creates a MYC-driven metabolic vulnerability
2024-03-16Ptip safeguards the epigenetic control of skeletal stem cell quiescence and potency in skeletogenesis
2024-02-29Fast and sensitive CRISPR detection by minimized interference of target amplification
2024-02-08Disulfiram ameliorates STING/MITA-dependent inflammation and autoimmunity by targeting RNF115
2024-01-24EGFR core fucosylation, induced by hepatitis C virus, promotes TRIM40-mediated-RIG-I ubiquitination and suppresses interferon-I antiviral defenses
2024-01-22Mic19 depletion impairs endoplasmic reticulum-mitochondrial contacts and mitochondrial lipid metabolism and triggers liver disease
2024-01-02m(6)A modification negatively regulates translation by switching mRNA from polysome to P-body via IGF2BP3
2023-12-21A novel antidiuretic hormone governs tumour-induced renal dysfunction
2023-12-06Targeting the epigenome to reinvigorate T cells for cancer immunotherapy
2023-12-04Mitochondrial DNA-triggered innate immune response: mechanisms and diseases
2023-12-01UVRAG cooperates with cargo receptors to assemble the ER-phagy site
2023-12-01HILPS, a long noncoding RNA essential for global oxygen sensing in humans
2023-11-24
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