科学研究
EGFR core fucosylation, induced by hepatitis C virus, promotes TRIM40-mediated-RIG-I ubiquitination and suppresses interferon-I antiviral defenses
2024-01-22Mic19 depletion impairs endoplasmic reticulum-mitochondrial contacts and mitochondrial lipid metabolism and triggers liver disease
2024-01-02m(6)A modification negatively regulates translation by switching mRNA from polysome to P-body via IGF2BP3
2023-12-21A novel antidiuretic hormone governs tumour-induced renal dysfunction
2023-12-06Targeting the epigenome to reinvigorate T cells for cancer immunotherapy
2023-12-04Mitochondrial DNA-triggered innate immune response: mechanisms and diseases
2023-12-01UVRAG cooperates with cargo receptors to assemble the ER-phagy site
2023-12-01HILPS, a long noncoding RNA essential for global oxygen sensing in humans
2023-11-24PD-1 signaling negatively regulates the common cytokine receptor γ chain via MARCH5-mediated ubiquitination and degradation to suppress anti-tumor immunity
2023-11-06KDM2B regulates hippocampal morphogenesis by transcriptionally silencing Wnt signaling in neural progenitors
2023-10-14A mitochondrial EglN1-AMPKα axis drives breast cancer progression by enhancing metabolic adaptation to hypoxic stress
2023-09-04Enhancement of the viability of T cells electroporated with DNA via osmotic dampening of the DNA-sensing cGAS-STING pathway
2023-07-27Fatty acid synthesis and oxidation regulate human endoderm differentiation by mediating SMAD3 nuclear localization via acetylation
2023-07-25STING is a cell-intrinsic metabolic checkpoint restricting aerobic glycolysis by targeting HK2
2023-07-13SCML2 contributes to tumor cell resistance to DNA damage through regulating p53 and CHK1 stability
2023-07-01
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