科学研究
Gut AstA mediates sleep deprivation-induced energy wasting in Drosophila
2023-05-23ERK and USP5 govern PD-1 homeostasis via deubiquitination to modulate tumor immunotherapy
2023-05-19Macrophages maintain mammary stem cell activity and mammary homeostasis via TNF-α-PI3K-Cdk1/Cyclin B1 axis
2023-05-02A desert lncRNA HIDEN regulates human endoderm differentiation via interacting with IMP1 and stabilizing FZD5 mRNA
2023-04-24The CEP170B-KIF2A complex destabilizes microtubule minus ends to generate polarized microtubule network
2023-04-04The super elongation complex drives transcriptional addiction in MYCN-amplified neuroblastoma
2023-03-29Resolving the lineage relationship between malignant cells and vascular cells in glioblastomas
2023-03-16Pax transactivation domain-interacting protein is required for preserving hematopoietic stem cell quiescence via regulating lysosomal activity
2023-03-16RNA helicase DHX15 exemplifies a unique dependency in acute leukemia
2023-03-02β-adrenoreceptor-triggered PKA activation negatively regulates the innate antiviral response
2023-02-01Dual-Responsive STAT3 Inhibitor Nanoprodrug Combined with Oncolytic Virus Elicits Synergistic Antitumor Immune Responses by Igniting Pyroptosis
2022-12-22Decoding m6A RNA methylome identifies PRMT6-regulated lipid transport promoting AML stem cell maintenance
2022-12-17Endocytosis triggers V-ATPase-SYK-mediated priming of cGAS activation and innate immune response
2022-10-25The E3 ubiquitin ligase ARIH1 promotes antiviral immunity and autoimmunity by inducing mono-ISGylation and oligomerization of cGAS
2022-10-13DNA topology regulates PAM-Cas9 interaction and DNA unwinding to enable near-PAMless cleavage by thermophilic Cas9
2022-10-10
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