科学研究
PD-1 signaling negatively regulates the common cytokine receptor γ chain via MARCH5-mediated ubiquitination and degradation to suppress anti-tumor immunity
2023-11-06KDM2B regulates hippocampal morphogenesis by transcriptionally silencing Wnt signaling in neural progenitors
2023-10-14A mitochondrial EglN1-AMPKα axis drives breast cancer progression by enhancing metabolic adaptation to hypoxic stress
2023-09-04Enhancement of the viability of T cells electroporated with DNA via osmotic dampening of the DNA-sensing cGAS-STING pathway
2023-07-27Fatty acid synthesis and oxidation regulate human endoderm differentiation by mediating SMAD3 nuclear localization via acetylation
2023-07-25STING is a cell-intrinsic metabolic checkpoint restricting aerobic glycolysis by targeting HK2
2023-07-13SCML2 contributes to tumor cell resistance to DNA damage through regulating p53 and CHK1 stability
2023-07-01Gut AstA mediates sleep deprivation-induced energy wasting in Drosophila
2023-05-23ERK and USP5 govern PD-1 homeostasis via deubiquitination to modulate tumor immunotherapy
2023-05-19Macrophages maintain mammary stem cell activity and mammary homeostasis via TNF-α-PI3K-Cdk1/Cyclin B1 axis
2023-05-02A desert lncRNA HIDEN regulates human endoderm differentiation via interacting with IMP1 and stabilizing FZD5 mRNA
2023-04-24The CEP170B-KIF2A complex destabilizes microtubule minus ends to generate polarized microtubule network
2023-04-04The super elongation complex drives transcriptional addiction in MYCN-amplified neuroblastoma
2023-03-29Resolving the lineage relationship between malignant cells and vascular cells in glioblastomas
2023-03-16Pax transactivation domain-interacting protein is required for preserving hematopoietic stem cell quiescence via regulating lysosomal activity
2023-03-16
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