A noncoding variant confers pancreatic differentiation defect and contributes to diabetes susceptibility by recruiting RXRA

A subset of neutrophils activates anti-tumor immunity and inhibits non-small-cell lung cancer progression

Epitope prime editing shields hematopoietic cells from CD123 immunotherapy for acute myeloid leukemia

Rapid generation of long, chemically modified pegRNAs for prime editing

Amplification editing enables efficient and precise duplication of DNA from short sequence to megabase and chromosomal scale

Minimizing the ratio of ionizable lipid in lipid nanoparticles for in vivo base editing

USP8-governed GPX4 homeostasis orchestrates ferroptosis and cancer immunotherapy

UFL1 ablation in T cells suppresses PD-1 UFMylation to enhance anti-tumor immunity